Client(OCI) Application Fails to Run: NL-08015: Client(OCI) Side Initialization Of Diagnosability Framework Failed & ORA-48165
Last updated on AUGUST 02, 2017
Applies to:Oracle Net Services - Version 188.8.131.52 and later
Information in this document applies to any platform.
ADR issue followiing installation of 12.2 client on Linux;
NL-08014: Failed to initialize Diagnosability framework, falling back to old network tracing/logging
NL-08015: Client(OCI) side initialization of Diagnosability framework failed
ORA-48165: user missing read, write, or exec permission on specified ADR Base directory 
User inputted base directory is invalid  [/u01/app/oracle] <===This is the setting for ADR_BASE specified in the sqlnet.ora file
This is a new installation of the Oracle client version 12.2
This issue may not reproduce using SQL*Plus.
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